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Chemagen chemagic MSM I

Chemagen chemagic Magnetic Separation Module I

The chemagic Magnetic Separation Module I (chemagic MSM I) enables fully automated nucleic acid isolation within one hour. Viral RNA can be simultaneously isolated from 96 nasal swab samples.

The Chemagen MSM-1 is an automated system for high-throughput isolation of nucleic acids (DNA/RNA).
It utilizes a patented magnetic bead technology, whereby magnetizable metal rods are immersed in process solutions to efficiently collect and resuspend the bound particles.

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Technical features & capacity

Throughput: The system is modular and can process 12, 24, or 96 samples simultaneously, depending on the rod head used.

Sample volume: Highly flexible, from 10 µl to 10 ml.

Processing times:
- 96 samples (small volumes): approx. 15–60 min.
- 24 samples (medium volumes): approx. 35–60 min.
- 12 samples (large volumes): approx. 45–60 min.

Technology: Particle resuspension is achieved by rotating the metal rods at up to 2,000 rpm, ensuring high yield and purity without cross-contamination.

System components & modules

Automation: The MSM-1 can be integrated into standard liquid-handling units and is often equipped with a 6-axis industrial robot for fully automated sample tracking.

Software: Operated via chemagic QA software (LIMS-compatible).

Applications
The device is primarily used in research and diagnostics, including:
- Biobanking and human genetics
- HLA typing
- Detection of viruses and bacteria
- Extraction from various sample types such as whole blood, saliva, serum, or plasma

System components
- Actuation: High-precision linear axes for vertical movement and a rotation axis for mixing
- Electromagnet: Central unit for controlling magnetic attraction on the metal rods
- Interfaces: Integrated PC with monitor, keyboard, and barcode scanner for sample traceability
- Software: chemagic QA software (LIMS-compatible, logging, user management)

Key features
- Cross-contamination protection: Single-use tip combs for the metal rods prevent contact between samples.
- Automation: Can be combined with the chemagic Dispenser for automated buffer filling or integrated into liquid-handling robots (e.g., Hamilton, Tecan).

Rod heads: 96
Sample volume: 10 - 400 μL
Number of samples: 1 to 96
TFT monitor, keyboard and mouse
Year of manufacture: 2007

Dimensions & setup
- Base unit (W/D/H): approx. 600 x 640 x 950 mm
- Carrier axis (W/D/H): 1940 x 170 x 200 mm (fully expanded with rail system)
- Total footprint: A fully configured system may require up to 2000 x 740 x 800 mm (L/W/H)

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